At the southern end of the Eyre Peninsula, Port Lincoln is a large fishing town idyllically set on the brilliant and expansive waters of Boston Bay. This beautiful natural harbour not only encourages a wealth of watersports such as sailing, water-skiing, swimming and fishing, but shelters Australia's largest tuna fishing fleet and the town's ultra modern tuna-farming operation. This culmination has seen Port Lincoln become the largest exporter of commercial fish in the country, and the community celebrates the start of the season every year by hosting the weird and wonderful Tunarama Festival.

Getting out on the area's waterways is not a problem, with a variety of charters and cruises operating out of Lincoln Cove. Boats with special viewing platforms provide lunch while extending an unparalleled look at at the impressive tuna farms. Larger vessels travel out to the sealion colonies on the off-shore islands, and some even go as far as the great white sharks breeding grounds off Dangerous Reef. In town, there are a number a historical exhibits and buildings open to anyone who's curious. Most notable is the Old Mill, whose elevated site offers sensational views over the bay. The town is also equipt with plenty of eating establishments, and the range of accommodation is as you would expect of any popular holiday destination.

Port Lincoln also makes the ideal base from which to explore the nearby Lincoln and Coffin Bay National Parks. Within easy striking distance to the south of town, the "Y" shaped Lincoln National Park is renowned for its untouched wilderness and breathtakingly rugged coastline of sheer cliff faces, sheltered coves, and impressive surf beaches. You'll need to get a pass from the parks office on Liverpool Street to enter, and those that wish to camp can acquire permits at the office as well. Less than thirty kilometres to the west of Port Lincoln, the coastal landscape encompassed by the Coffin Bay Natural Park is equally spectacular to its eastern neighbour, and access to its beauty lies just of the Flinders Highway via the tiny holiday hamlet of Coffin Bay. Coffin Bay is a picturesque little town worth a visit in own right, offering great fishing and swimming in its nearby estuary, which also happens to produce some of the best oysters in the country.

Travelling beyond Coffin Bay, the Flinders Highway begins its journey up the Great Australian Bight side of the Eyre Peninsula. A majority of the route runs about ten kilometres inland, passing by the vast salt pans of the Greenly, Malata, and Hamilton Lakes before finally touching the coast at Elliston. Elliston is a small fishing town whose tranquil setting on Waterloo Bay have led it to become a quietly popular holiday destination. Views of the bay are available from the town's cliff top walk, and the rest of the area's striking coastline can be soaked in via scenic drives, running both north and south of the town centre. The Elliston area's is also one of several good salmon fishing spots along this side of the peninsula.

Just up the road from Elliston is Venus Bay. A picturesque seaside holiday town which sits on a narrow peninsula overlooking Venus Bay and its islands. It is quiet, peaceful and friendly and its tranquil sheltered waters provide an absolute mecca for the small boat and jetty fisherman as well as water-skiing, swimming, canoeing or sailing. The town lookout offers breathtaking views of towering cliffs and booming surf rolling in from the Great Australian Bight. Keen board riders can also view surf conditions of nearby surf beaches from here.

Approximately eighty kilometres north-west of Elliston, the strange pink rock formations (technically speaking their inselbergs) by the highway known as "Murphy's Haystacks", make for unusual photo opportunity en route to Streaky Bay. Streaky Bay is another gorgeous little fishing town come quiet seaside resort, beautifully set on the stunning natural harbour of the same name. When the explorer Matthew Flinders first sailed into the bay in the early 19th century, long strands of seaweed created a streaking effect in the lucid waters, and lo and behold, the town's name was born. While in Streaky Bay, seafood lovers will adore the area's succulent oysters, and surfers should check out the break at Back Beach. Overlooking the bay, good meals, ale, and atmosphere can all be found at the flash and friendly Streaky Bay Community Hotel/Motel.

From Streaky Bay, the Flinders Highway begins its final 100 kilometre stretch northwards, before rejoining the Eyre Highway just eight kilometres east of Ceduna (see Outback). On the Eyre Highway 209 kilometres west of Ceduda, the township of Wudinna is a favoured stopping point for those taking the barren inland route across the Eyre Peninsula.